The key is to limit your downside and have unlimited upside.

Investors
John Paulson
Born in 1955 in New York, John Paulson rose from obscurity managing a modest merger-arbitrage hedge fund to global fame by deploying credit default swaps to short subprime mortgage securities ahead of the 2007 crisis, personally earning roughly four billion dollars in a single year. The trade, chronicled in Gregory Zuckerman's book, is widely regarded as the greatest in financial history.
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John Paulson's Other Quotes
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Know what you own, and know why you own it.
-- Peter Lynch
Invest in what you know.
-- Peter Lynch
You can't predict. You can prepare.
-- Howard Marks
The most important thing is being attentive to cycles.
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The most important investment decision you will make is how to allocate your assets.
-- David F. Swensen
Investors should pay attention to what they own, not simply to the overall return of their portfolio.
-- David F. Swensen